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We are located on the 10th floor of Smilow Center for Translational Research at Penn.

We take multi-pronged interdisciplinary approaches (Biochemistry, Biophysics, Cell Biology, Genetics and Molecular Biology) to dissect the role of protein homeostasis in vivo and in disease models. We are particularly interested in uncovering the intimate link that must exist between different components of the cellular protein homeostasis pathway.

It is our belief that knowledge gained from our endeavors will not only advance the basic understanding of protein homeostasis in the broader context of biology, but will also open up new therapeutic opportunities against those diseases that arise secondary to accumulation of “toxic” proteins such as cancer and neurodegenerative diseases, to alleviate human suffering.

If you are interested in joining our family or simply interested in our work, please leave us a message and we will get back to you as soon as possible.

Our research programs are supported by